The Alpha-1 Translational Research Laboratory is devoted to characterizing the molecular mechanisms responsible for the development of liver and lung disease in AAT Deficient individuals and to the development of new treatments.

Current projects include (click for abstracts):

Mapping the Role of Unfolded Protein Response Genes in Hepatocytes Expressing Z Alpha-1-Antitrypsin
Funded by a Grant from the Alpha-1 Foundation

Tobacco Smoke-Induced Cell Injury in Lung Compartments
Funded by a Grant from the State of Florida Department of Health

Identification of Rare Alpha-1-Antitrypsin Gene Mutations by High Resolution DNA Melt Analysis

The role of apoptosis in lung inflammation and injury in alpha-1-antitrypsin deficiency
Funded by a Grant from the Alpha-1 Foundation

 

 
Alpha-1 Research Program -
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